[{"data":1,"prerenderedAt":65},["ShallowReactive",2],{"q-nurse-114-3-basic-medicine-021":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":34,"lastmod":64},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-114-3-基礎醫學-021","nurse-114-3-basic-medicine-021",114,3,21,"有關發炎反應的媒介物（mediators of inflammation），下列何者不是花生四烯酸（arachidonic acid）的代謝物？",{"A":15,"B":16,"C":17,"D":18},"血栓素 A 2 （thromboxane A 2 ）","前列腺素 D 2 （prostaglandin D 2 ）","白三烯素 D 4 （leukotriene D 4 ）","組織胺（histamine）","D",null,[],"本題考點在於花生四烯酸代謝路徑的產物辨識,屬反向題,要挑出『不是』其代謝物者。花生四烯酸經環氧合酶(COX)途徑生成前列腺素(prostaglandin,含PGD₂)與血栓素A₂(thromboxane A₂),經脂氧合酶(LOX)途徑生成白三烯素(leukotriene,含LTD₄),故A、B、C皆為其代謝物。組織胺(histamine)則由組胺酸經組胺酸脫羧酶生成、儲存於肥大細胞與嗜鹼性球顆粒內,並非花生四烯酸代謝物,故錯誤敘述為D,選D。","花生四烯酸由膜磷脂經磷脂酶A₂釋出後分兩路:COX路走前列腺素與血栓素(NSAID抑制此路)、LOX路走白三烯(氣喘用leukotriene拮抗劑作用於此)。組織胺屬『預先合成』的胺類介質、與花生四烯酸『現做』的類二十碳酸(eicosanoid)介質分屬不同來源,是本題常設的鑑別陷阱。",[25,27,30,32],{"term":26,"count":11},"花生四烯酸代謝",{"term":28,"count":29},"環氧合酶與脂氧合酶",1,{"term":31,"count":29},"前列腺素與血栓素",{"term":33,"count":29},"組織胺來源",[35,39,45,50,55,60],{"webId":36,"stem":37,"number":38,"year":10,"session":11},"nurse-114-3-basic-medicine-022","全身性紅斑性狼瘡（systemic lupus erythematosus, SLE）所造成的血球數目低下（cytopenia）病變，主要與下列何種過敏反應有關？",22,{"webId":40,"stem":41,"number":42,"year":43,"session":44},"nurse-115-2-basic-medicine-018","下列那一種條件會導致腎絲球過濾率下降？",18,115,2,{"webId":46,"stem":47,"number":48,"year":49,"session":29},"nurse-106-1-basic-medicine-062","下列何種藥物作用不會增加體重？",62,106,{"webId":51,"stem":52,"number":53,"year":54,"session":44},"nurse-107-2-basic-medicine-020","下列那一腦區受損將使人失去害怕的感覺？",20,107,{"webId":56,"stem":57,"number":58,"year":59,"session":44},"nurse-108-2-basic-medicine-064","服用下列何種藥物，須注意病人的視力是否有異常？",64,108,{"webId":61,"stem":62,"number":42,"year":63,"session":29},"nurse-110-1-basic-medicine-018","以間隙接合（gap junction）形成的電性突觸（electrical synapse）並不存在於：",110,"2026-09-04",1788510761110]