[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-114-1-basic-medicine-036":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":32,"lastmod":63},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-114-1-基礎醫學-036","nurse-114-1-basic-medicine-036",114,1,36,"Abciximab治療不穩定型心絞痛（unstable angina）的藥理機制為何？",{"A":15,"B":16,"C":17,"D":18},"cyclic nucleotide phosphodiesterase抑制劑","GP IIb\u002FIIIa 抑制劑","cyclooxygenase I 抑制劑","P2Y 12 ADP receptor 拮抗劑","B",null,[],"本題考點在於 abciximab 的抗血小板藥理機制。依藥理分類，abciximab 是針對血小板表面糖蛋白 GP IIb\u002FIIIa 受體的單株抗體片段，阻斷纖維蛋白原與該受體結合，從而抑制血小板聚集這一最終共同途徑，用於不穩定型心絞痛與經皮冠狀動脈介入，故選 B。A 為 cilostazol 等磷酸二酯酶抑制劑機制；C 為 aspirin 的 COX-1 抑制；D 為 clopidogrel 等 P2Y₁₂ 拮抗劑機制，皆非 abciximab。","GP IIb\u002FIIIa 是血小板聚集的最終共同路徑，故此類藥抗血小板效力最強。記憶對比：aspirin 擋 COX、clopidogrel 擋 ADP 受體、abciximab（-mab 為單株抗體）直接封鎖 GP IIb\u002FIIIa 最終出口；同類尚有 eptifibatide、tirofiban。",[25,27,28,30],{"term":26,"count":11},"abciximab",{"term":16,"count":11},{"term":29,"count":11},"血小板聚集",{"term":31,"count":11},"不穩定型心絞痛",[33,37,42,48,53,58],{"webId":34,"stem":35,"number":36,"year":10,"session":11},"nurse-114-1-basic-medicine-037","下列何種藥物最適合以吸入方式用於緩解急性氣喘（asthma）發作？",37,{"webId":38,"stem":39,"number":40,"year":10,"session":41},"nurse-114-3-basic-medicine-033","嗎啡（morphine）的止痛作用主要是活化下列何種受體而產生？",33,3,{"webId":43,"stem":44,"number":45,"year":46,"session":47},"nurse-115-2-basic-medicine-027","關於食道靜脈曲張的敘述，下列何者錯誤？",27,115,2,{"webId":49,"stem":50,"number":51,"year":52,"session":11},"nurse-107-1-basic-medicine-015","下列何者支配耳下腺（parotid gland）的分泌？",15,107,{"webId":54,"stem":55,"number":56,"year":57,"session":11},"nurse-108-1-basic-medicine-059","下列 NSAIDs 藥物中，何者產生出血的機會最低？",59,108,{"webId":59,"stem":60,"number":61,"year":62,"session":47},"nurse-109-2-basic-medicine-013","膽汁之製造及注入消化道的位置，下列何者正確？",13,109,"2026-09-04",1788510756539]