[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-114-1-basic-medicine-031":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":33,"lastmod":63},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":27},"nurse-114-1-基礎醫學-031","nurse-114-1-basic-medicine-031",114,1,31,"下列何種藥物不能抑制乙醯膽鹼酯酶（acetylcholinesterase）？",{"A":15,"B":16,"C":17,"D":18},"physostigmine","sarin","edrophonium","bethanechol","D",null,[],"本題考點在於區分乙醯膽鹼酯酶抑制劑與直接型膽鹼受體致效劑，本題為反向題，要找出「不能」抑制此酶者。依藥理分類，physostigmine 與 edrophonium 皆為可逆性乙醯膽鹼酯酶抑制劑，sarin 為不可逆的有機磷神經毒劑，三者都抑制此酶；而 bethanechol 是直接作用於蕈毒鹼受體的致效劑，並不抑制酶，故選 D。","乙醯膽鹼酯酶抑制劑使突觸內乙醯膽鹼堆積而放大副交感作用；bethanechol 則跳過酶、直接刺激受體，臨床用於術後腸道或膀胱無力。記憶要點：字尾 -stigmine 多為抑制劑，sarin 屬有機磷（不可逆、需 pralidoxime 解毒），bethanechol 的 -chol 提示直接膽鹼致效。",[25,28,29,31],{"term":26,"count":27},"乙醯膽鹼酯酶抑制劑",2,{"term":18,"count":11},{"term":30,"count":11},"蕈毒鹼受體致效劑",{"term":32,"count":11},"有機磷",[34,38,43,48,53,58],{"webId":35,"stem":36,"number":37,"year":10,"session":11},"nurse-114-1-basic-medicine-032","下列藥物中，何者對於改善酒精成癮治療沒有幫助？",32,{"webId":39,"stem":40,"number":41,"year":10,"session":42},"nurse-114-3-basic-medicine-028","有關乳房纖維腺瘤（fibroadenoma），下列敘述何者最不適當？",28,3,{"webId":44,"stem":45,"number":46,"year":47,"session":27},"nurse-115-2-basic-medicine-022","第一型過敏反應是因人體的那一種抗體與抗原結合後，造成肥大細胞的去顆粒化作用，而釋出組織胺（histamine）？",22,115,{"webId":49,"stem":50,"number":51,"year":52,"session":11},"nurse-107-1-basic-medicine-010","男性尿道，由尿道口為近端至遠端貫穿下列構造的順序為何？①尿道海綿體 ②泌尿生殖橫膈 ③前列腺",10,107,{"webId":54,"stem":55,"number":56,"year":57,"session":11},"nurse-108-1-basic-medicine-054","有關抗癌藥物之敘述，下列何者錯誤？",54,108,{"webId":59,"stem":60,"number":61,"year":62,"session":27},"nurse-109-2-basic-medicine-008","拔牙前，醫生進行局部麻醉以阻斷下列何者之傳導來減少疼痛？",8,109,"2026-09-04",1788510756492]