[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-113-1-basic-medicine-006":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":33,"lastmod":63},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-113-1-基礎醫學-006","nurse-113-1-basic-medicine-006",113,1,6,"科林菲特氏症（Klinefelter's syndrome）患者的白血球細胞核旁，最多可以看到幾個巴氏體（barr body）？",{"A":15,"B":16,"C":17,"D":18},"0","1","2","3","B",null,[],"本題考點在於巴氏體（Barr body）數目與 X 染色體數的關係。依 Lyon 假說，體細胞中多餘的 X 染色體會去活化形成巴氏體，巴氏體數目＝X 染色體數減 1。科林菲特氏症（Klinefelter's syndrome）核型為 47,XXY，含兩條 X 染色體，故巴氏體數為 2−1＝1 個，選 B。A 為 0 對應僅一條 X（如正常男性 XY）；C 為 2 需三條 X（如 XXX 或 48,XXXY）；D 為 3 需四條 X，皆不符 XXY。故選 B。","計算口訣：『巴氏體＝X 數 − 1』。正常女性 XX 有 1 個巴氏體，正常男性 XY 為 0；Klinefelter（XXY）為 1；Turner（45,X）為 0；XXX 為 2。X 去活化是劑量補償機制，使兩性 X 基因表現量相當。此題只要記住核型 XXY 有兩個 X，即可推出答案。",[25,27,29,31],{"term":26,"count":11},"Barr body計算",{"term":28,"count":11},"Lyon假說X去活化",{"term":30,"count":11},"Klinefelter核型47XXY",{"term":32,"count":11},"劑量補償",[34,38,42,47,53,58],{"webId":35,"stem":36,"number":37,"year":10,"session":11},"nurse-113-1-basic-medicine-007","下列何者最可能同時降低動脈血壓波振幅（arterial pulse wave）與動脈血壓波速度（pulse wave velocity）？",7,{"webId":39,"stem":40,"number":41,"year":10,"session":41},"nurse-113-3-basic-medicine-003","支配聲帶肌群的神經是：",3,{"webId":43,"stem":44,"number":45,"year":46,"session":11},"nurse-114-1-basic-medicine-047","有關花斑癬（Pityriasis versicolor）之敘述，下列何者正確？",47,114,{"webId":48,"stem":49,"number":50,"year":51,"session":52},"nurse-115-2-basic-medicine-045","金黃色葡萄球菌（Staphylococcus aureus）若懸浮於人類的血漿中會促進纖維蛋白（fibrin）形成引發凝血，與下列那一種毒素最相關？",45,115,2,{"webId":54,"stem":55,"number":56,"year":57,"session":11},"nurse-107-1-basic-medicine-039","下列關於慢性氣喘（asthma）所引起的病理變化，何者錯誤？",39,107,{"webId":59,"stem":60,"number":61,"year":62,"session":11},"nurse-108-1-basic-medicine-073","關於類鐸受體（Toll-like receptor, TLR）的敘述，下列何者正確？",73,108,"2026-09-04",1788510749407]