[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-112-1-basic-medicine-037":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":33,"lastmod":63},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-112-1-基礎醫學-037","nurse-112-1-basic-medicine-037",112,1,37,"治療高血脂症時，能同時降低膽固醇及三酸甘油酯的藥物，下列何者最佳？",{"A":15,"B":16,"C":17,"D":18},"Atorvastatin（Lipitor）","Cholestyramine（Questran）","Colestipol（Colestid）","Nicotinic acid（Niacin）","D",null,[],"本題考點在於降血脂藥的作用譜。菸鹼酸（Nicotinic acid／Niacin）能同時降低膽固醇（LDL）與三酸甘油酯（TG），並升高 HDL，作用最全面，故選 D。考點在於排除其他：A Atorvastatin（statin 類）主要抑制 HMG-CoA 還原酶、強力降 LDL 膽固醇，但降三酸甘油酯效果相對有限；B Cholestyramine 與 C Colestipol 皆為膽酸結合樹脂，只降 LDL 膽固醇，且可能反而使三酸甘油酯上升，不符「同時降兩者」。故以兼降膽固醇與三酸甘油酯而言，菸鹼酸最佳。","菸鹼酸抑制脂肪組織脂解、減少肝臟 VLDL 合成，故 TG 與 LDL 皆降、HDL 升，屬全方位調脂。副作用為臉部潮紅（prostaglandin 前列腺素媒介，可先服阿斯匹靈減輕）。對比：statin 主降 LDL；fibrate 主降 TG；樹脂類降 LDL 但升 TG。記憶點：niacin＝「三高全包，就是會臉紅」。可連結血脂異常分類與各類藥物選擇複習。",[25,27,29,31],{"term":26,"count":11},"菸鹼酸 Niacin",{"term":28,"count":11},"同時降膽固醇與三酸甘油酯",{"term":30,"count":11},"膽酸結合樹脂",{"term":32,"count":11},"statin 類降血脂藥",[34,38,43,49,54,59],{"webId":35,"stem":36,"number":37,"year":10,"session":11},"nurse-112-1-basic-medicine-038","下列何種藥物可降低腸道中水分的分泌，用於治療旅行時之腹瀉？",38,{"webId":39,"stem":40,"number":41,"year":10,"session":42},"nurse-112-3-basic-medicine-034","下列有關 Propranolol 特性和作用之敘述，何者錯誤？",34,3,{"webId":44,"stem":45,"number":46,"year":47,"session":48},"nurse-113-2-basic-medicine-028","生骨性（osteoblastic）骨轉移，最常見於下列何種腫瘤？",28,113,2,{"webId":50,"stem":51,"number":52,"year":53,"session":42},"nurse-114-3-basic-medicine-026","家族腺瘤性瘜肉症（familial adenomatous polyposis）主要是因為那個基因產生突變所造成？",26,114,{"webId":55,"stem":56,"number":57,"year":58,"session":11},"nurse-106-1-basic-medicine-080","下列有關廣東住血線蟲（Angiostrongylus cantonensis）之敘述，何者正確？",80,106,{"webId":60,"stem":61,"number":41,"year":62,"session":48},"nurse-107-2-basic-medicine-034","下列何者最不容易造成全身性血栓性栓塞（systemic thromboembolism）之栓子（embolus）？",107,"2026-09-04",1788510740797]