[{"data":1,"prerenderedAt":65},["ShallowReactive",2],{"q-nurse-111-1-basic-medicine-065":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":33,"lastmod":64},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-111-1-基礎醫學-065","nurse-111-1-basic-medicine-065",111,1,65,"在淋巴結的濾泡（follicle）所聚集的細胞，會產生什麼特殊蛋白質？",{"A":15,"B":16,"C":17,"D":18},"肝素（heparin）","抗體（antibody）","穿孔素／顆粒溶解酶（perforin／granzyme）","纖維分解酶（cellulase）","B",null,[],"本題考點為淋巴結濾泡（follicle）內聚集細胞的產物。淋巴結濾泡是 B 淋巴球聚集與生發中心（germinal center）所在，B 細胞在此增殖、分化為漿細胞並產生抗體（antibody），故選 B。A 的肝素由肥大細胞與嗜鹼性球分泌，與濾泡 B 細胞無關。C 的穿孔素／顆粒溶解酶由細胞毒性 T 細胞與 NK 細胞產生，屬細胞毒殺作用。D 的纖維分解酶（cellulase）是分解纖維素的酵素，人體並不產生。故濾泡與 B 細胞、抗體對應。","淋巴結分區記憶：皮質（cortex）含淋巴濾泡＝B 細胞區，內有生發中心（抗原刺激後 B 細胞增殖、體細胞高突變、類別轉換、親和力成熟）；副皮質（paracortex）＝T 細胞區（含樹突細胞呈遞抗原）；髓質（medulla）含漿細胞與巨噬細胞。抗體由分化成熟的漿細胞（plasma cell）分泌。口訣：『濾泡＝B＝抗體工廠』。Perforin\u002Fgranzyme 是 CTL 與 NK 的殺手武器，屬另一條免疫路線。",[25,27,29,31],{"term":26,"count":11},"淋巴結濾泡",{"term":28,"count":11},"B 淋巴球\u002F生發中心",{"term":30,"count":11},"抗體(漿細胞產生)",{"term":32,"count":11},"淋巴結分區",[34,38,43,48,53,59],{"webId":35,"stem":36,"number":37,"year":10,"session":11},"nurse-111-1-basic-medicine-066","下列關於細胞激素（cytokine）的敘述何者錯誤？",66,{"webId":39,"stem":40,"number":41,"year":42,"session":11},"nurse-112-1-basic-medicine-032","下列何者不是短效性鎮靜安眠藥？",32,112,{"webId":44,"stem":45,"number":46,"year":42,"session":47},"nurse-112-3-basic-medicine-026","下列何者不是動脈粥狀硬化（arteriosclerosis）的高危險因子？",26,3,{"webId":49,"stem":50,"number":51,"year":52,"session":11},"nurse-114-1-basic-medicine-024","下列何者並非鉛中毒的常見表現？",24,114,{"webId":54,"stem":55,"number":56,"year":57,"session":58},"nurse-115-2-basic-medicine-028","下列何者為腎病症候群（nephrotic syndrome）最主要的變化？",28,115,2,{"webId":60,"stem":61,"number":62,"year":63,"session":11},"nurse-107-1-basic-medicine-012","下列何者供應闌尾的血液？",12,107,"2026-09-04",1788510733267]