[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-110-2-medical-surgical-039":3},{"subject":4,"subjectSlug":5,"subjectFullName":4,"question":6,"related":33,"lastmod":63},"內外科護理學","medical-surgical",{"id":7,"webId":8,"year":9,"session":10,"subject":4,"number":11,"stem":12,"options":13,"answer":18,"answerNote":19,"images":20,"explanation":21,"explanationDeep":22,"topics":23,"freq":10},"nurse-110-2-內外科護理學-039","nurse-110-2-medical-surgical-039",110,2,39,"有關化學治療特性的敘述，下列何者正確？",{"A":14,"B":15,"C":16,"D":17},"使用具細胞毒性藥物來縮小腫瘤或控制症狀","化學治療藥物大多可以通過血腦屏障","使用多種不同抗癌藥物來增加療效，但副作用也會增加","目前治療方式多採高劑量、較無毒性，減少次數、增加休息時間方式進行","A",null,[],"本題考點在於化學治療的基本特性。化學治療是利用具細胞毒性的藥物干擾癌細胞分裂增殖，以縮小腫瘤、控制症狀或清除微轉移，故A正確。多數化療藥物分子特性使其「不易」通過血腦屏障，這也是中樞神經常成為藥物庇護所的原因，故B「大多可通過血腦屏障」錯。合併多種藥物的目的是利用不同機轉、減少抗藥性並在「不重疊毒性」下增效，並非單純增加副作用，B、C的敘述取向不符設計原意，故C錯。D「高劑量、較無毒性、減少次數」自相矛盾且不符實務，錯。故正確為A。","化療打擊快速分裂細胞，故正常快速分裂組織(骨髓、黏膜、毛囊、生殖細胞)易受累而生副作用。血腦屏障限制多數藥物進入中樞，故中樞白血病須鞘內注射。合併化療選用機轉不同、毒性不重疊、皆具療效的藥物以增效並減抗藥。記憶口訣「化療打分裂快的、過不了腦屏障、合併求增效減抗藥」。可連結概念：細胞週期特異性藥物、鞘內化療、抗藥機轉。",[24,26,29,31],{"term":25,"count":10},"細胞毒性藥物",{"term":27,"count":28},"化學治療",1,{"term":30,"count":28},"血腦屏障",{"term":32,"count":28},"合併化療原則",[34,38,43,47,53,58],{"webId":35,"stem":36,"number":37,"year":9,"session":10},"nurse-110-2-medical-surgical-040","有關瀕死病人護理的敘述，下列何者正確？①出現瀕死前的嘎嘎聲是因為喉嚨有痰，要給予抽痰 ②肛門附近周圍皮膚傷口可使用氧化鋅 ③要鼓勵病人進食，以增加舒適感 ④瀕死病人對刺激無反應時，其聽力也會喪失 ⑤意識不清病人宜採側臥，以利分泌物流出",40,{"webId":39,"stem":40,"number":41,"year":42,"session":28},"nurse-111-1-medical-surgical-056","照護右上肺葉肺炎病人之護理措施，下列何者不適當？",56,111,{"webId":44,"stem":45,"number":46,"year":42,"session":10},"nurse-111-2-medical-surgical-070","有關抗利尿激素分泌不當症候群（SIADH）的護理指導，下列何者錯誤？",70,{"webId":48,"stem":49,"number":50,"year":51,"session":52},"nurse-112-3-medical-surgical-028","有關頭頸部放射治療對口腔造成的影響，下列處置何者正確？",28,112,3,{"webId":54,"stem":55,"number":56,"year":57,"session":28},"nurse-114-1-medical-surgical-032","病人因車禍送到急診，身體評估出現下列何者時，應懷疑可能有氣胸？",32,114,{"webId":59,"stem":60,"number":61,"year":62,"session":10},"nurse-115-2-medical-surgical-026","有關乳癌之相關敘述，下列何者最不適當？",26,115,"2026-09-04",1788510729143]