[{"data":1,"prerenderedAt":67},["ShallowReactive",2],{"q-nurse-110-2-basic-medicine-073":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":36,"lastmod":66},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-110-2-基礎醫學-073","nurse-110-2-basic-medicine-073",110,2,73,"關於土倫法蘭西斯桿菌（Francisella tularensi）的敘述，下列何者正確？",{"A":15,"B":16,"C":17,"D":18},"對清除細菌來說，抗體免疫比細胞免疫重要","A 型菌比 B 型菌的毒性強","可利用乙內醯胺（β-lactam）類抗生素降低死亡率","主要引發戰壕熱（trench fever）","B",null,[],"本題考點為土倫法蘭西斯桿菌（Francisella tularensis）的特性，屬選正確題。考點在於辨識其分型毒力差異：A 型（tularensis 亞種）毒性較強、致死率較高，B 型（holarctica）較弱，故選 B。A 錯，此菌為胞內菌，清除主要倚賴細胞性（T 細胞）免疫而非抗體；C 錯，β-lactam 類對此菌效果不佳，治療首選為 aminoglycoside 類如 streptomycin、gentamicin；D 錯，戰壕熱由五日熱巴通氏菌（Bartonella quintana）引起，非本菌所致。","Francisella tularensis 為革蘭氏陰性、兼性胞內寄生的小球桿菌，感染劑量極低、可經皮膚、吸入或病媒（蜱、鹿蠅）傳播，屬高危生物恐怖劑。胞內菌的清除靠巨噬細胞活化與 Th1 細胞免疫，這也是選項 A「抗體比細胞免疫重要」被判錯的關鍵。治療以胺基醣苷為主、四環素或氟喹諾酮為替代。記憶法：兔熱病＝胞內菌＝靠細胞免疫＋胺基醣苷。可連結概念：胞內菌清除機轉、生物恐怖劑分級、病媒傳染病鑑別。",[25,27,30,32,34],{"term":26,"count":11},"Francisella tularensis",{"term":28,"count":29},"A 型毒性較強",1,{"term":31,"count":29},"胞內菌與細胞免疫",{"term":33,"count":29},"aminoglycoside 治療",{"term":35,"count":29},"兔熱病",[37,41,46,51,56,61],{"webId":38,"stem":39,"number":40,"year":10,"session":11},"nurse-110-2-basic-medicine-074","關於肉毒梭孢桿菌（Clostridium botulinum）感染之敘述，下列何者錯誤？",74,{"webId":42,"stem":43,"number":44,"year":45,"session":11},"nurse-111-2-basic-medicine-010","有關舌乳頭之敘述，下列何者正確？",10,111,{"webId":47,"stem":48,"number":49,"year":50,"session":11},"nurse-112-2-basic-medicine-004","下列何者無法執行閉口的動作？",4,112,{"webId":52,"stem":53,"number":11,"year":54,"session":55},"nurse-113-3-basic-medicine-002","下列何者受坐骨神經（sciatic nerve）支配？",113,3,{"webId":57,"stem":58,"number":59,"year":60,"session":29},"nurse-115-1-basic-medicine-006","神經細胞於靜止膜電位階段，細胞膜對鈉離子與鉀離子的通透性為何？",6,115,{"webId":62,"stem":63,"number":64,"year":65,"session":11},"nurse-106-2-basic-medicine-020","下列何種神經傳遞物質，生成後並不儲存於突觸囊泡內？",20,106,"2026-09-04",1788510727949]