[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-110-1-basic-medicine-080":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":34,"lastmod":63},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-110-1-基礎醫學-080","nurse-110-1-basic-medicine-080",110,1,80,"下列何種藥物治療蟠尾絲蟲（Onchocerca volvulus）引起的河川盲（river blindness）為首選藥物，而且病人副作用最小？",{"A":15,"B":16,"C":17,"D":18},"Tetracycline","Ivermectin","Praziquantel","Mebendazole","B",null,[],"本題考點是蟠尾絲蟲症(河川盲)的首選藥物。依寄生蟲治療原則，Ivermectin能有效殺死微絲蟲、控制蟠尾絲蟲(Onchocerca volvulus)引起的河川盲，且病人副作用相對輕微，為首選藥，故選B。Tetracycline屬抗菌四環素、非抗絲蟲主力；Praziquantel主要治血吸蟲與絛蟲；Mebendazole針對腸道線蟲感染。三者皆非河川盲首選，答案為B。","機轉延伸：Ivermectin作用於無脊椎動物特有的麩胺酸調控氯離子通道，使蟲體神經肌肉過度極化而麻痺，因人類無此通道故選擇性高、副作用小。用藥時須留意殺蟲後微絲蟲大量死亡引發的發炎(Mazzotti reaction)。近年常合併doxycycline清除共生的Wolbachia以增療效，此為考點延伸。",[25,27,29,30,32],{"term":26,"count":11},"蟠尾絲蟲",{"term":28,"count":11},"河川盲",{"term":16,"count":11},{"term":31,"count":11},"麩胺酸氯離子通道",{"term":33,"count":11},"微絲蟲",[35,39,44,48,53,58],{"webId":36,"stem":37,"number":11,"year":10,"session":38},"nurse-110-2-basic-medicine-001","細胞膜的成分，下列何者錯誤？",2,{"webId":40,"stem":41,"number":42,"year":43,"session":11},"nurse-111-1-basic-medicine-017","碳水化合物（carbohydrate）的碳、氫、氧原子數目的比率是：",17,111,{"webId":45,"stem":46,"number":47,"year":43,"session":38},"nurse-111-2-basic-medicine-031","Amantadine 具有抗巴金森氏症的作用，有關其副作用，下列敘述何者錯誤？",31,{"webId":49,"stem":50,"number":51,"year":52,"session":11},"nurse-113-1-basic-medicine-029","進行性多灶性白質腦病（progressive multifocal leukoencephalopathy, PML）是一種髓鞘脫失（demyelination）的病變，臨床上常與免疫抑制有關。此病主要由何種病毒引起？",29,113,{"webId":54,"stem":55,"number":56,"year":57,"session":38},"nurse-114-2-basic-medicine-033","下列降血壓藥物中，何者為腎素抑制劑（renin inhibitor）？",33,114,{"webId":59,"stem":60,"number":61,"year":62,"session":11},"nurse-106-1-basic-medicine-027","下列有關血壓的敘述，何者錯誤？",27,106,"2026-09-04",1788510719855]