[{"data":1,"prerenderedAt":66},["ShallowReactive",2],{"q-nurse-109-2-basic-medicine-076":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":34,"lastmod":65},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":27},"nurse-109-2-基礎醫學-076","nurse-109-2-basic-medicine-076",109,2,76,"下列關於痲瘋分枝桿菌（Mycobacterium leprae）的敘述，何者正確？",{"A":15,"B":16,"C":17,"D":18},"是人畜共通的致病菌，可由動物傳染給人","細菌生長緩慢，可用人工培養基進行體外培養","感染細菌之後可分為類結核型痲瘋（tuberculoid leprosy）和痲瘋瘤型痲瘋（lepromatous leprosy），前者皮膚病變通常較後者明顯","目前以多重藥物合併療法（multidrug therapy）治療痲瘋分枝桿菌之感染","D",null,[],"本題考點為痲瘋分枝桿菌的培養特性與治療。依世界衛生組織的治療準則,痲瘋以多重藥物合併療法(MDT)治療,可減少抗藥性,故 D 正確,選 D。A 錯誤,痲瘋主要為人與人間長期接觸傳染,非典型人畜共通病。B 錯誤,M. leprae 至今無法以人工培養基體外培養,須靠動物模式(如犰狳、鼠足墊)繁殖。C 錯誤,類結核型屬少菌型、皮膚病灶較侷限;痲瘋瘤型屬多菌型、病灶廣泛而明顯,兩者敘述相反。考點在於辨識其不可人工培養與 MDT 治療原則。","M. leprae 偏好較低溫組織,侵犯皮膚與周邊神經,造成感覺喪失與變形。免疫光譜:類結核型(TT)細胞免疫強、菌少、肉芽腫明顯;痲瘋瘤型(LL)細胞免疫弱、菌量多、病灶瀰漫。MDT 標準組合為 dapsone、rifampin、clofazimine。記憶:結核型=菌少病灶少(強免疫壓制),瘤型=菌多病灶多(免疫失守)。",[25,28,30,32],{"term":26,"count":27},"痲瘋分枝桿菌",1,{"term":29,"count":27},"無法人工培養",{"term":31,"count":27},"多重藥物合併療法 MDT",{"term":33,"count":27},"類結核型 vs 痲瘋瘤型",[35,39,44,49,54,60],{"webId":36,"stem":37,"number":38,"year":10,"session":11},"nurse-109-2-basic-medicine-077","下列何種真菌會產生萌芽管（germ tube）？",77,{"webId":40,"stem":41,"number":42,"year":43,"session":11},"nurse-110-2-basic-medicine-013","腎小體（renal corpuscle）的過濾膜（filtration membrane），不含下列那一構造？",13,110,{"webId":45,"stem":46,"number":47,"year":48,"session":27},"nurse-111-1-basic-medicine-027","下列何者不屬於胰臟的外分泌蛋白質？",27,111,{"webId":50,"stem":51,"number":52,"year":53,"session":11},"nurse-112-2-basic-medicine-045","下列何種自體免疫疾病，病人體內會有 IgG 抗體對抗腎臟基底膜上第四型膠原蛋白，引起腎組織內的發炎反應？",45,112,{"webId":55,"stem":56,"number":57,"year":58,"session":59},"nurse-113-3-basic-medicine-049","下列有關腸病毒的描述何者錯誤？",49,113,3,{"webId":61,"stem":62,"number":63,"year":64,"session":27},"nurse-115-1-basic-medicine-043","下列何種細胞最主要表現 MHC class II 分子，並將抗原呈現給 T 細胞？",43,115,"2026-09-04",1788510715404]