[{"data":1,"prerenderedAt":66},["ShallowReactive",2],{"q-nurse-109-1-basic-medicine-048":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":35,"lastmod":65},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-109-1-基礎醫學-048","nurse-109-1-basic-medicine-048",109,1,48,"庫辛氏病（Cushing’s disease）的原因為何？",{"A":15,"B":16,"C":17,"D":18},"長期服用類固醇","腦下腺（pituitary gland）分泌過多腎上腺皮質刺激素（adrenocorticotropic hormone；ACTH）","腎上腺皮質增生（adrenal cortical hyperplasia）","肺癌細胞分泌過多的腎上腺皮質刺激素","B",null,[],"本題考點是庫辛氏「病」的特定病因定義。庫辛氏病（Cushing's disease）特指腦下腺（腦下垂體）分泌過多腎上腺皮質刺激素（ACTH），刺激腎上腺皮質過度分泌皮質醇所致，故選 B。(A) 長期服用類固醇屬外源性庫辛氏「症候群」，非庫辛氏「病」。(C) 腎上腺皮質增生或腺瘤自主分泌皮質醇屬腎上腺性（ACTH 非依賴性）庫辛氏症候群，非庫辛氏病。(D) 肺癌等異位分泌 ACTH 屬異位性 ACTH 症候群，亦非庫辛氏病。故庫辛氏病專指腦下腺 ACTH 過多，答案為 B。","務必分辨「庫辛氏症候群（Cushing syndrome）」與「庫辛氏病（Cushing disease）」：症候群是皮質醇過高的總稱，病因含外源類固醇（最常見）、腎上腺腫瘤、異位 ACTH（如小細胞肺癌）；「病」則專指腦下腺 ACTH 腺瘤（ACTH 依賴性、內源最常見）。臨床：月亮臉、水牛肩、中心性肥胖、紫紋、高血糖、高血壓、骨鬆。鑑別靠 ACTH 高低與地塞米松抑制試驗（高劑量可抑制者傾向腦下腺源）。記憶：「病＝腦下腺，症候群＝所有原因」，本題正是考此定義。",[25,27,29,31,33],{"term":26,"count":11},"庫辛氏病",{"term":28,"count":11},"腦下腺ACTH腺瘤",{"term":30,"count":11},"腎上腺皮質刺激素ACTH",{"term":32,"count":11},"庫辛氏症候群",{"term":34,"count":11},"地塞米松抑制試驗",[36,40,45,50,55,60],{"webId":37,"stem":38,"number":39,"year":10,"session":11},"nurse-109-1-basic-medicine-049","有關抗高血壓藥物的敘述，下列何者錯誤？",49,{"webId":41,"stem":42,"number":43,"year":10,"session":44},"nurse-109-2-basic-medicine-065","當體細胞受到病毒感染後，主要啟動下列何種細胞的功能，可以有效的控制病情？",65,2,{"webId":46,"stem":47,"number":48,"year":49,"session":11},"nurse-110-1-basic-medicine-079","下列何種酵素與麴菌屬（Aspergillus）之毒性無關？",79,110,{"webId":51,"stem":52,"number":53,"year":54,"session":44},"nurse-111-2-basic-medicine-037","下列何種藥物是藉由周邊作用來抑制咳嗽反射，作為治療咳嗽的藥物？",37,111,{"webId":56,"stem":57,"number":58,"year":59,"session":11},"nurse-113-1-basic-medicine-041","下列何種構造通常是由多醣組成，對於幫助細菌抵抗免疫細胞的吞噬作用（phagocytosis）極為重要？",41,113,{"webId":61,"stem":62,"number":63,"year":64,"session":44},"nurse-114-2-basic-medicine-035","關於 Diphenhydramine 的敘述，下列何者錯誤？",35,114,"2026-09-04",1788510711316]