[{"data":1,"prerenderedAt":66},["ShallowReactive",2],{"q-nurse-108-1-basic-medicine-037":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":35,"lastmod":65},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-108-1-基礎醫學-037","nurse-108-1-basic-medicine-037",108,1,37,"長期服用止痛劑如阿斯匹靈（aspirin）或乙醯胺酚（acetaminophen）造成的止痛劑腎病（analgesic nephropathy）常伴隨腎臟那一個部位的壞死？",{"A":15,"B":16,"C":17,"D":18},"腎皮質","腎絲球","腎小管及間質","腎莢膜","C",null,[],"本題考點為止痛劑腎病的病理部位。依病理，長期使用非類固醇止痛劑（如阿斯匹靈）或乙醯胺酚，會抑制前列腺素使腎髓質血流減少，並產生氧化代謝物直接毒害腎組織，導致腎乳頭壞死與慢性腎小管間質腎炎，故壞死主要在腎小管及間質（C）。腎皮質（A）壞死多見於嚴重休克或產科大出血；腎絲球（B）損傷屬腎絲球腎炎範疇；腎莢膜（D）為包覆腎臟的結締組織被膜，與止痛劑毒性無關，皆非答案。","止痛劑腎病典型為『腎乳頭壞死』併慢性間質性腎炎。機轉：前列腺素本負責維持腎髓質血流，NSAID 抑制前列腺素合成使髓質缺血；acetaminophen 代謝物在髓質高濃度下產生氧化壓力。腎乳頭因血流原本就稀少，最易缺血壞死。記憶：止痛劑傷『小管間質＋乳頭』。",[25,27,29,31,33],{"term":26,"count":11},"止痛劑腎病",{"term":28,"count":11},"腎乳頭壞死",{"term":30,"count":11},"慢性間質性腎炎",{"term":32,"count":11},"前列腺素與腎髓質血流",{"term":34,"count":11},"NSAID",[36,40,45,50,55,60],{"webId":37,"stem":38,"number":39,"year":10,"session":11},"nurse-108-1-basic-medicine-038","下列有關乳癌的敘述何者錯誤？",38,{"webId":41,"stem":42,"number":43,"year":10,"session":44},"nurse-108-2-basic-medicine-054","下列何種藥物可減少糖分的吸收？",54,2,{"webId":46,"stem":47,"number":48,"year":49,"session":11},"nurse-109-1-basic-medicine-068","下列針對 Bacillus cereus 造成的疾病，何者正確？",68,109,{"webId":51,"stem":52,"number":53,"year":54,"session":44},"nurse-110-2-basic-medicine-026","有關排卵過程的敘述，下列何者正確？",26,110,{"webId":56,"stem":57,"number":58,"year":59,"session":11},"nurse-112-1-basic-medicine-020","下列有關吸氣時的敘述，何者錯誤？",20,112,{"webId":61,"stem":62,"number":63,"year":64,"session":44},"nurse-113-2-basic-medicine-014","下列何種激素的分泌對血糖濃度的影響最小？",14,113,"2026-09-04",1788510708420]