[{"data":1,"prerenderedAt":65},["ShallowReactive",2],{"q-nurse-107-2-basic-medicine-047":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":34,"lastmod":64},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":27},"nurse-107-2-基礎醫學-047","nurse-107-2-basic-medicine-047",107,2,47,"下列那種甲狀腺癌的腫瘤細胞的細胞核常呈清澈樣（clear）或有假包涵體（pseudo-inclusions）？",{"A":15,"B":16,"C":17,"D":18},"乳突性癌（papillary carcinoma）","濾泡性癌（follicular carcinoma）","髓質癌（medullary carcinoma）","未分化癌（anaplastic carcinoma）","A",null,[],"本題考點是甲狀腺癌的細胞核型態鑑別。依內分泌病理,乳突性甲狀腺癌的診斷以「細胞核特徵」為關鍵——核呈清澈毛玻璃樣（clear／ground-glass,又稱 Orphan Annie eye 核)、有核溝與核內假包涵體（pseudo-inclusions),故選 A。B 濾泡性癌診斷靠有無包膜或血管侵犯,核型態較平凡,不具上述特徵。C 髓質癌源自濾泡旁 C 細胞,特徵是澱粉樣物質沉積與分泌降鈣素,非清澈核。D 未分化癌細胞高度異型、多形性巨細胞,惡性度極高,亦非以清澈核假包涵體為特徵。","核特徵記憶——乳突性癌:清澈「孤兒安妮眼」核（Orphan Annie eye)、核溝（nuclear groove)、核內假包涵體、砂粒體（psammoma body);常經淋巴轉移但預後相對好。對比:濾泡性癌＝看包膜／血管侵犯、易血行轉移;髓質癌＝C 細胞來源、降鈣素↑、澱粉樣物、與 MEN2 及 RET 基因相關;未分化癌＝老年、快速增大、預後最差。診斷邏輯口訣:「乳突看核、濾泡看膜」。可連結:砂粒體、降鈣素、MEN2、RET 原癌基因。",[25,28,30,32],{"term":26,"count":27},"乳突性甲狀腺癌",1,{"term":29,"count":27},"清澈毛玻璃樣核",{"term":31,"count":27},"核內假包涵體",{"term":33,"count":27},"髓質癌澱粉樣物對比",[35,39,44,48,53,58],{"webId":36,"stem":37,"number":38,"year":10,"session":11},"nurse-107-2-basic-medicine-048","40 歲女性，有全身疲倦、輕度發燒及關節僵硬，特別是清晨起床時，左右手指及肘關節。抽血檢查發現有類風濕性因子（rheumatoid factor）。這位女性最有可能罹患下列何者疾病？",48,{"webId":40,"stem":41,"number":42,"year":43,"session":27},"nurse-108-1-basic-medicine-064","下列何種反轉錄酶（reverse transcriptase）抑制劑，不適用於人類免疫不全病毒（HIV）感染的治療？",64,108,{"webId":45,"stem":46,"number":47,"year":43,"session":11},"nurse-108-2-basic-medicine-078","下列何種不是常見感染皮膚、毛髮及指甲（cutaneous mycoses）的黴菌？",78,{"webId":49,"stem":50,"number":51,"year":52,"session":27},"nurse-110-1-basic-medicine-036","下列何者不屬於 B 細胞（B lymphocyte）腫瘤？",36,110,{"webId":54,"stem":55,"number":56,"year":57,"session":27},"nurse-111-1-basic-medicine-080","宿主細胞的何種機轉必為病毒所用？",80,111,{"webId":59,"stem":60,"number":61,"year":62,"session":63},"nurse-112-3-basic-medicine-044","下列何者並非葡萄球菌腸毒素引起的食物中毒之特徵？",44,112,3,"2026-09-04",1788510723737]