[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-107-1-basic-medicine-053":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":34,"lastmod":63},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":27},"nurse-107-1-基礎醫學-053","nurse-107-1-basic-medicine-053",107,1,53,"Buspirone 用於廣泛性焦慮症（generalized anxiety disorder）之慢性治療（chronic treatment），是因為該藥主要作用於何種受體所致？",{"A":15,"B":16,"C":17,"D":18},"Acetylcholine","Alpha-adrenoceptor","GABA","Serotonin（5-HT）","D",null,[],"本題考點是 Buspirone 的受體作用機轉。Buspirone 為血清素(serotonin, 5-HT)系統藥物,作用為 5-HT1A 受體的部分促效劑,藉調節血清素傳遞達抗焦慮效果,適合廣泛性焦慮症的慢性治療,故選 D。A Acetylcholine 受體與其抗焦慮機轉無關;B Alpha-adrenoceptor 屬正腎上腺素系統,非其主要標的;C GABA 是 benzodiazepine 的作用受體,而 buspirone 正因不作用於 GABA,故無鎮靜、依賴與戒斷問題,選項 C 錯誤。","Buspirone 特色:選擇性 5-HT1A 部分促效,無鎮靜、無肌肉鬆弛、無成癮性、不與酒精加成,但需連續服用 1–2 週才起效,故僅適合慢性焦慮而非急性恐慌。對照 benzodiazepine 走 GABA-A\u002F氯離子路徑,起效快但有耐受依賴。記憶:『buspirone=血清素路、慢工出細活、不上癮』。",[25,28,30,32],{"term":26,"count":27},"Buspirone",2,{"term":29,"count":11},"5-HT1A 部分促效劑",{"term":31,"count":11},"血清素(5-HT)",{"term":33,"count":11},"廣泛性焦慮症",[35,39,43,48,53,58],{"webId":36,"stem":37,"number":38,"year":10,"session":11},"nurse-107-1-basic-medicine-054","在耳鼻喉科與家醫科門診，針對過敏性鼻炎與氣喘患者，處方以 Zileuton 治療，此藥物主要抑制下列何種酵素？",54,{"webId":40,"stem":41,"number":42,"year":10,"session":27},"nurse-107-2-basic-medicine-070","臘腸桿菌毒素（Botulinum toxin）可以用於美容除皺之機制為何？",70,{"webId":44,"stem":45,"number":46,"year":47,"session":27},"nurse-108-2-basic-medicine-004","下列何者附著於肱骨的內上髁（medial epicondyle）？",4,108,{"webId":49,"stem":50,"number":51,"year":52,"session":27},"nurse-109-2-basic-medicine-042","下列有關空氣污染中，懸浮微粒（particulate matter；PM）的敘述，何者錯誤？",42,109,{"webId":54,"stem":55,"number":56,"year":57,"session":11},"nurse-111-1-basic-medicine-006","下列支氣管樹的分支，何者具有氣體交換功能？",6,111,{"webId":59,"stem":60,"number":61,"year":62,"session":27},"nurse-112-2-basic-medicine-020","腸泌素對胰島素的分泌屬於下列何種調控機制？",20,112,"2026-09-04",1788510701381]