[{"data":1,"prerenderedAt":64},["ShallowReactive",2],{"q-nurse-107-1-basic-medicine-047":3},{"subject":4,"subjectSlug":5,"subjectFullName":6,"question":7,"related":33,"lastmod":63},"基礎醫學","basic-medicine","基礎醫學(包括解剖學、生理學、病理學、藥理學、微生物學與免疫學)",{"id":8,"webId":9,"year":10,"session":11,"subject":4,"number":12,"stem":13,"options":14,"answer":19,"answerNote":20,"images":21,"explanation":22,"explanationDeep":23,"topics":24,"freq":11},"nurse-107-1-基礎醫學-047","nurse-107-1-basic-medicine-047",107,1,47,"下列甲狀腺病變中，何者的細胞核呈現出毛玻璃樣（ground-glass）的變化，且有明顯的核溝（nuclear groove）？",{"A":15,"B":16,"C":17,"D":18},"濾泡狀癌（follicular carcinoma）","髓狀癌（medullary carcinoma）","橋本氏甲狀腺炎（Hashimoto thyroiditis）","乳頭狀癌（papillary carcinoma）","D",null,[],"本題考點是甲狀腺乳頭狀癌的核特徵。乳頭狀癌(papillary carcinoma)的細胞核呈毛玻璃樣(ground-glass, Orphan Annie eye)、有核溝(nuclear groove)與核內假包涵體,是其病理診斷依據,故選 D。A 濾泡狀癌以血管或包膜侵犯判斷惡性,核不呈毛玻璃樣;B 髓狀癌源自濾泡旁 C 細胞、間質有澱粉樣沉積並分泌降鈣素;C 橋本氏甲狀腺炎為自體免疫發炎,見淋巴球浸潤與 Hürthle 細胞,均無乳頭狀癌的特徵性核變化。","乳頭狀癌是最常見的甲狀腺癌,診斷靠『核』特徵而非乳頭結構本身:毛玻璃核、核溝、核內假包涵體、砂粒體(psammoma body)。預後佳,主要經淋巴轉移至頸部淋巴結。對照:濾泡狀癌走血行轉移(肺、骨);髓狀癌測 calcitonin 與 CEA、可能屬 MEN2;未分化癌(anaplastic)惡性度最高。記憶:『Orphan Annie 眼+核溝=乳頭狀』。",[25,27,29,31],{"term":26,"count":11},"甲狀腺乳頭狀癌",{"term":28,"count":11},"毛玻璃核(Orphan Annie)",{"term":30,"count":11},"核溝",{"term":32,"count":11},"砂粒體",[34,38,43,48,53,58],{"webId":35,"stem":36,"number":37,"year":10,"session":11},"nurse-107-1-basic-medicine-048","下列那一個中樞神經系統部位是肌萎縮性側索硬化症（amyotrophic lateral sclerosis）的主要病變區？",48,{"webId":39,"stem":40,"number":41,"year":10,"session":42},"nurse-107-2-basic-medicine-064","下列何種免疫製劑，可以阻斷病毒複製及增強宿主免疫力，在臨床上用於治療 B 型肝炎？",64,2,{"webId":44,"stem":45,"number":46,"year":47,"session":11},"nurse-108-1-basic-medicine-078","下列有關白色念珠菌（Candida albicans）之敘述何者錯誤？",78,108,{"webId":49,"stem":50,"number":51,"year":52,"session":42},"nurse-109-2-basic-medicine-036","下列那一個心臟腔室發生原發性腫瘤的機率最高？",36,109,{"webId":54,"stem":55,"number":56,"year":57,"session":42},"nurse-110-2-basic-medicine-080","下列何種寄生蟲病診斷時不需要檢查糞便檢體？",80,110,{"webId":59,"stem":60,"number":61,"year":62,"session":42},"nurse-112-2-basic-medicine-014","生長激素對胰島素代謝有何影響？",14,112,"2026-09-04",1788510701311]