[{"data":1,"prerenderedAt":63},["ShallowReactive",2],{"q-nurse-106-2-psychiatric-community-019":3},{"subject":4,"subjectSlug":5,"subjectFullName":4,"question":6,"related":33,"lastmod":62},"精神科與社區衛生護理學","psychiatric-community",{"id":7,"webId":8,"year":9,"session":10,"subject":4,"number":11,"stem":12,"options":13,"answer":18,"answerNote":19,"images":20,"explanation":21,"explanationDeep":22,"topics":23,"freq":26},"nurse-106-2-精神科與社區衛生護理學-019","nurse-106-2-psychiatric-community-019",106,2,19,"臨床上採用 Aricept 作為治療阿茲海默症初、中期的記憶障礙，其主要作用機轉為何？",{"A":14,"B":15,"C":16,"D":17},"改善腦部血循環","抑制抗膽鹼酯酶","增加乙醯膽鹼代謝","改善體液電解質濃度","B",null,[],"本題考點為 Aricept（donepezil）治療阿茲海默症的作用機轉。依其藥理分類，donepezil 屬乙醯膽鹼酯酶抑制劑，透過抑制分解乙醯膽鹼的酵素（即抑制膽鹼酯酶），提高突觸間乙醯膽鹼濃度以改善認知，故正解為 B「抑制抗膽鹼酯酶」（意指抑制膽鹼酯酶）。A 錯在改善腦部血循環是另一類促智藥的作用，非其機轉。C 錯在增加乙醯膽鹼「代謝」方向相反，donepezil 是減少乙醯膽鹼被分解，而非增加代謝。D 錯在改善體液電解質濃度與膽鹼系統機轉無關。","阿茲海默症的膽鹼假說：基底前腦膽鹼神經元退化、乙醯膽鹼不足導致認知下降。膽鹼酯酶抑制劑（donepezil、rivastigmine、galantamine）用於輕中度，透過抑制 AChE 使乙醯膽鹼停留更久。重度則加用 NMDA 受體拮抗劑 memantine。記憶要訣：Aricept＝「擋住分解酵素→乙醯膽鹼變多」，選項 C 的「增加代謝」是反向陷阱。常見副作用來自膽鹼過多：噁心、腹瀉、心搏過緩、多涎。",[24,27,29,31],{"term":25,"count":26},"Donepezil(Aricept)",1,{"term":28,"count":26},"乙醯膽鹼酯酶抑制劑",{"term":30,"count":26},"膽鹼假說",{"term":32,"count":26},"乙醯膽鹼",[34,38,43,47,52,57],{"webId":35,"stem":36,"number":37,"year":9,"session":10},"nurse-106-2-psychiatric-community-020","黃先生，診斷思覺失調症，表示自己是調查局南機組幹員，被派到公司臥底，最近他查到公司與某位政府高層有進行一項見不得光的交易，所以被下降頭，護理師的反應下列何者最適當？",20,{"webId":39,"stem":40,"number":41,"year":42,"session":26},"nurse-107-1-psychiatric-community-036","陳小姐接受社區復健方案，護理師協助她連結社區相關資源，此時護理師最主要發揮那一項專業角色？",36,107,{"webId":44,"stem":45,"number":46,"year":42,"session":10},"nurse-107-2-psychiatric-community-050","引起護理師下背痛的主要危險因子為何種類型？",50,{"webId":48,"stem":49,"number":50,"year":51,"session":10},"nurse-109-2-psychiatric-community-008","阿雄國小三年級，自從父母離婚後，與母親相依為命，但於母親再婚後出現翹課、不參加活動，顯得鬰鬰寡歡，母親極為苦惱而接受家庭治療的幫助，有關其家庭治療的主要目的，下列何項正確？ ①矯正個人性格的偏差 ②改善家庭功能 ③協助家庭改善問題 ④改善家庭成員的互動",8,109,{"webId":53,"stem":54,"number":55,"year":56,"session":10},"nurse-110-2-psychiatric-community-052","有關社區健康評估的目的，下列何者不適當？",52,110,{"webId":58,"stem":59,"number":60,"year":61,"session":26},"nurse-112-1-psychiatric-community-006","有關電氣痙攣療法之敘述，下列何者最適宜？",6,112,"2026-09-04",1788510700029]